Flo was spayed 3 months after her first season. We didn't give her any medication for pain. She was given a 24 hour pain relief injection just before we picked her up by the vet. I think a dog may be a bit nervy, anxious and want cuddles for a few days as they must feel rotten and not know why and just want to feel protected by you - I know the first night I had to take Flo to sleep with me and she didn't sleep unless being cuddled - I suppose they must feel like they've been attached and want to feel safe to relax. She was quiet and careful in her movements for about 2 weeks but completely back to her old self (no change in personality) by say 4 weeks. It does take a while to recover from this major operation.